Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LMP744 is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 736.00 | |
50 mg | 6-8 weeks | $ 957.00 | |
100 mg | 6-8 weeks | $ 1,440.00 |
Description | LMP744 is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity. |
In vitro | LMP744 (0.1-5 μM, 3 days) induces dose-dependent accumulation of cells in the S and G2 phases of the cell cycle[2].The GI50 value of LMP744 for NCI60 cells is 0.1 μM[2]. |
In vivo | LMP744 ?(10-50 mg/kg) administered i.v. push once a week for 4 weeks in nude mice moderately actives against FaDu tumor xenografts??and human A253 without significant toxicity[1]. |
Synonyms | NSC706744, MJ-III65 |
Molecular Weight | 452.46 |
Formula | C24H24N2O7 |
CAS No. | 308246-52-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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LMP744 308246-52-8 Others LMP-744 NSC-706744 LMP 744 NSC 706744 NSC706744 MJ-III65 inhibitor inhibit