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LSN 3213128

LSN 3213128
LSN 3213128, anti-tumor activity. is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells.
Catalog No. T11884Cas No. 1941211-99-9
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LSN 3213128

Catalog No. T11884Cas No. 1941211-99-9
LSN 3213128, anti-tumor activity. is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
25 mg$1,4306-8 weeks
50 mg$1,8606-8 weeks
100 mg$2,5006-8 weeks
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Product Introduction

Bioactivity
Description
LSN 3213128, anti-tumor activity. is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells.
Targets&IC50
AICARFT (cells):19 nM , AICARFT:16 nM
Chemical Properties
Molecular Weight409.45
FormulaC17H16FN3O4S2
Cas No.1941211-99-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 62.5 mg/mL (152.64 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4423 mL12.2115 mL24.4230 mL122.1150 mL
5 mM0.4885 mL2.4423 mL4.8846 mL24.4230 mL
10 mM0.2442 mL1.2212 mL2.4423 mL12.2115 mL
20 mM0.1221 mL0.6106 mL1.2212 mL6.1058 mL
50 mM0.0488 mL0.2442 mL0.4885 mL2.4423 mL
100 mM0.0244 mL0.1221 mL0.2442 mL1.2212 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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