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Lenalidomide-C5-NH2

Name: Lenalidomide-C5-NH2
Brand: TargetMol
SKU: T17928
Price: 43 USD
Availability: InStock
Rating: 4.5 (1 reviews)

Catalog No. T17928Cas No. 2093388-45-3

Alias E3 ligase Ligand-Linker Conjugates 31, Cereblon Ligand-Linker Conjugates 19

Lenalidomide-C5-NH2 is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to form PROTACs[1].

Lenalidomide-C5-NH2

Catalog No. T17928Alias E3 ligase Ligand-Linker Conjugates 31, Cereblon Ligand-Linker Conjugates 19Cas No. 2093388-45-3

Lenalidomide-C5-NH2 is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to form PROTACs[1].

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500 mg	Inquiry	Backorder

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Product Introduction

Bioactivity

Description	Lenalidomide-C5-NH2 is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to form PROTACs[1].
Alias	E3 ligase Ligand-Linker Conjugates 31, Cereblon Ligand-Linker Conjugates 19

Chemical Properties

Molecular Weight	329.39
Formula	C₁₈H₂₃N₃O₃
Cas No.	2093388-45-3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 5 mg/mL (15.18 mM), Sonication is recommended.

H2O: 50 mg/mL (151.80 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	3.0359 mL	15.1796 mL	30.3591 mL	151.7957 mL
5 mM	0.6072 mL	3.0359 mL	6.0718 mL	30.3591 mL
10 mM	0.3036 mL	1.5180 mL	3.0359 mL	15.1796 mL

H2O

	1mg	5mg	10mg	50mg
20 mM	0.1518 mL	0.7590 mL	1.5180 mL	7.5898 mL
50 mM	0.0607 mL	0.3036 mL	0.6072 mL	3.0359 mL
100 mM	0.0304 mL	0.1518 mL	0.3036 mL	1.5180 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Lenalidomide C5 NH2Lenalidomide-C-5-NH2Lenalidomide-C5-NH2LenalidomideC5NH2