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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | N-(Azido-PEG3)-N-bis(PEG3-acid) is a polyethylene glycol (PEG)-based linker that incorporates an azido group and two PEG3-acid moieties, widely applicable in the synthesis of proteolysis targeting chimeras (PROTACs) for the selective degradation of target proteins[1]. |
In vitro | PROTACs consist of two ligands linked together: one binds to an E3 ubiquitin ligase, and the other to the target protein. These compounds leverage the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins[1]. |
Molecular Weight | 626.69 |
Formula | C26H50N4O13 |
Cas No. | 2055042-57-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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