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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs) [1]. |
In vitro | PROTACs consist of two distinct ligands linked by a connector: one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Alias | n-methyl-n-methyl-o-m-peg4-o-propargyl-peg4-cy3 |
Molecular Weight | 829.46 |
Formula | C45H65ClN2O10 |
Cas No. | 2107273-62-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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