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NH-bis(C1-PEG1-Boc)

Catalog No. T18480Cas No. 2171072-53-8

NH-bis(C1-PEG1-Boc) is an alkyl/ether-based PROTAC linker used for PROTAC synthesis[1].

NH-bis(C1-PEG1-Boc)

NH-bis(C1-PEG1-Boc)

Catalog No. T18480Cas No. 2171072-53-8
NH-bis(C1-PEG1-Boc) is an alkyl/ether-based PROTAC linker used for PROTAC synthesis[1].
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2 mg$495 days
5 mg$77Backorder
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Product Introduction

Bioactivity
Description
NH-bis(C1-PEG1-Boc) is an alkyl/ether-based PROTAC linker used for PROTAC synthesis[1].
In vitro
PROTACs consist of two ligands joined by a linker: one ligand binds to an E3 ubiquitin ligase, while the other targets the protein. These compounds leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Chemical Properties
Molecular Weight347.45
FormulaC17H33NO6
Cas No.2171072-53-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

NH-bis(C1-PEG1-Boc)NHbis(C1PEG1Boc)NH bis(C1 PEG1 Boc)NH-bis(C-1-PEG1-Boc)
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