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NH2-Ph-C4-acid-NH2-Me

Catalog No. T18624Cas No. 1263819-48-2
Alias PROTAC Linker 31

NH2-Ph-C4-acid-NH2-Me (PROTAC Linker 31) is an alkyl chain-based compound used in the synthesis of PROTACs [1].

NH2-Ph-C4-acid-NH2-Me

NH2-Ph-C4-acid-NH2-Me

Catalog No. T18624Alias PROTAC Linker 31Cas No. 1263819-48-2
NH2-Ph-C4-acid-NH2-Me (PROTAC Linker 31) is an alkyl chain-based compound used in the synthesis of PROTACs [1].
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Product Introduction

Bioactivity
Description
NH2-Ph-C4-acid-NH2-Me (PROTAC Linker 31) is an alkyl chain-based compound used in the synthesis of PROTACs [1].
In vitro
PROTACs are composed of two distinct ligands connected by a linker: one binds to an E3 ubiquitin ligase, and the other targets a specific protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1].
AliasPROTAC Linker 31
Chemical Properties
Molecular Weight222.28
FormulaC12H18N2O2
Cas No.1263819-48-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

NH-2-Ph-C4-acid-NH2-MeNH2PhC4acidNH2MeNH2 Ph C4 acid NH2 MeNH2-Ph-C4-acid-NH2-Me
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