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ODM-204

Catalog No. T12289   CAS 1642818-64-1

ODM-204 is novel nonsteroidal dual inhibitor of both androgen receptor and CYP17A1 enzyme(IC50s of 80 nM and 22 nM, respectively).

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ODM-204 Chemical Structure
ODM-204, CAS 1642818-64-1
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Biological Description
Chemical Properties
Storage & Solubility Information
Description ODM-204 is novel nonsteroidal dual inhibitor of both androgen receptor and CYP17A1 enzyme(IC50s of 80 nM and 22 nM, respectively).
Targets&IC50 CYP17A1 enzyme:22 nM , Androgen Receptor:80 nM
Molecular Weight 374.4
Formula C20H21F3N4
CAS No. 1642818-64-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Oksala R, et al. Discovery and development of ODM-204: A Novel nonsteroidal compound for the treatment of castration-resistant prostate cancer by blocking the androgen receptor and inhibiting CYP17A1. J Steroid Biochem Mol Biol. 2018 Feb 10. pii: S0960-0760(18)30078-5.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

ODM-204 1642818-64-1 Others ODM204 ODM 204 inhibitor inhibit

 

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