Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SK1-IN-1 is a potent inhibitor of sphingosine kinase 1 (SPHK1)(IC50 of 58 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 6-8 weeks | $ 364.00 | |
25 mg | 6-8 weeks | $ 1,450.00 | |
50 mg | 6-8 weeks | $ 1,890.00 | |
100 mg | 6-8 weeks | $ 2,800.00 |
Description | SK1-IN-1 is a potent inhibitor of sphingosine kinase 1 (SPHK1)(IC50 of 58 nM). |
Targets&IC50 | SPHK1:58 nM |
In vivo | SK1-IN-1 shows significant improvement in the intrinsic clearance, particularly against human liver microsomes. SK1-IN-1 is selected for rat PK studies and demonstrates modest in oral bioavailability with acceptable half-lives in blood circulation. |
Molecular Weight | 398.5 |
Formula | C22H30N4O3 |
CAS No. | 1218816-71-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (250.94 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
SK1-IN-1 1218816-71-7 GPCR/G Protein S1P Receptor SK-1-IN-1 SK1IN1 SK1 IN 1 inhibitor inhibit