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SKF-107457

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Catalog No. T26192Cas No. 126333-28-6
Alias SKF 107457, Ala-Ala-Phepsi(CH(OH)CH2)Gly-Val-Val-OCH3

SKF-107457 is an HIV protease type 1 inhibitor. It is a hexapeptide substrate analog with the scissile bond being replaced by a hydroxy ethylene isostere.

SKF-107457
Other Forms of SKF-107457:
Skf 107457T34654144285-77-8
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SKF-107457

😃Good
Catalog No. T26192Alias SKF 107457, Ala-Ala-Phepsi(CH(OH)CH2)Gly-Val-Val-OCH3Cas No. 126333-28-6
SKF-107457 is an HIV protease type 1 inhibitor. It is a hexapeptide substrate analog with the scissile bond being replaced by a hydroxy ethylene isostere.
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Product Introduction

Bioactivity
Description
SKF-107457 is an HIV protease type 1 inhibitor. It is a hexapeptide substrate analog with the scissile bond being replaced by a hydroxy ethylene isostere.
AliasSKF 107457, Ala-Ala-Phepsi(CH(OH)CH2)Gly-Val-Val-OCH3
Chemical Properties
Molecular Weight577.723
FormulaC29H47N5O7
Cas No.126333-28-6
Relative Density.1.31g/cm3
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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SKF107457SKF-107457
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