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Tos-PEG7-OH, a PEG-based linker for PROTACs, connects two essential ligands vital for the formation of PROTAC molecules, thereby facilitating selective protein degradation through the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Tos-PEG7-OH, a PEG-based linker for PROTACs, connects two essential ligands vital for the formation of PROTAC molecules, thereby facilitating selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other targeting the desired protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 480.57 |
Formula | C21H36O10S |
Cas No. | 1028089-05-5 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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