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Triacsin C

Name: Triacsin C
Brand: TargetMol
SKU: T13199
Price: 39 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T13199Cas No. 76896-80-5

Alias WS 1228A, FR 900190

Triacsin C (WS 1228A) from Streptomyces aureofaciens is a differential inhibitor of arachidonic acid coenzyme A synthetase and non-specific long-chain acyl-coenzyme A synthetase, with anti-atherosclerotic activity, inhibition of ACSL activity, and inhibition of the accumulation of TAGs into lipid droplets (LDs).Triacsin C has been used to study rotavirus infection and Alzheimer;s disease. Triacsin C is used to study rotavirus infection and Alzheimer;s disease.

Triacsin C

😃Good

Catalog No. T13199Alias WS 1228A, FR 900190Cas No. 76896-80-5

Pack Size	Price	Availability	Quantity
500 μg	Inquiry	35 days
1 mg	Inquiry	35 days

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COA

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Product Introduction

Bioactivity

Description	Triacsin C (WS 1228A) from Streptomyces aureofaciens is a differential inhibitor of arachidonic acid coenzyme A synthetase and non-specific long-chain acyl-coenzyme A synthetase, with anti-atherosclerotic activity, inhibition of ACSL activity, and inhibition of the accumulation of TAGs into lipid droplets (LDs).Triacsin C has been used to study rotavirus infection and Alzheimer;s disease. Triacsin C is used to study rotavirus infection and Alzheimer;s disease.
Targets&IC50	CpACS1:3.70 μM, CpACS2:2.32 μM
In vivo	In interleukin knockout mice infected with Cryptosporidium, Triacsin C (8-15 mg/kg/d; oral gavage; 1 week) reduced parasite oocyst production by up to 88.1% with no apparent toxicity[3].
Alias	WS 1228A, FR 900190

Chemical Properties

Molecular Weight	207.27
Formula	C₁₁H₁₇N₃O
Cas No.	76896-80-5
Smiles	CCC/C=C/C/C=C/C=C/C=N/NN=O
Relative Density.	0.94 g/cm3

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 2 mg/mL (9.65 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.8246 mL	24.1231 mL	48.2462 mL	241.2312 mL
5 mM	0.9649 mL	4.8246 mL	9.6492 mL	48.2462 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Triacsin Clong-chain acyl-CoA synthetase 4FR-900190FR900190ACSL