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Vapendavir diphosphate

Vapendavir diphosphate
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Vapendavir diphosphate

Catalog No. T13284Cas No. 1198151-75-5
Vapendavir diphosphate is a potent enteroviral capsid binder (CB) and has a potent antiviral activity for enterovirus 71 (EV71) replication (EC50: 0.5-1.4 μM in different EV71 strains).
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Pack SizePriceAvailabilityQuantity
25 mg$6706-8 weeks
50 mg$8716-8 weeks
100 mg$1,4706-8 weeks
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Product Introduction

Bioactivity
Description
Vapendavir diphosphate is a potent enteroviral capsid binder (CB) and has a potent antiviral activity for enterovirus 71 (EV71) replication (EC50: 0.5-1.4 μM in different EV71 strains).
In vitro
In vitro, Vapendavir efficiently inhibit the replication of 21 EV71 strains/isolates that are representative of the different genogroups A, B, and C[2].
AliasBTA798 diphosphate
Chemical Properties
Molecular Weight578.45
FormulaC21H32N4O11P2
Cas No.1198151-75-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 6.75 mg/mL (11.67 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7288 mL8.6438 mL17.2876 mL86.4379 mL
5 mM0.3458 mL1.7288 mL3.4575 mL17.2876 mL
10 mM0.1729 mL0.8644 mL1.7288 mL8.6438 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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