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ZM 449829

ZM 449829
ZM 449829 is an effective, selective inhibitor of Janus tyrosine kinase 3 which binds competitively to the JAK3 ATP site (pIC50: 6.8, 5.0, 4.7, and < 5.0 for JAK3, EGFR, JAK1 and CDK4 respectively).
Catalog No. T23564Cas No. 4452-06-6

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ZM 449829

Catalog No. T23564Cas No. 4452-06-6

ZM 449829 is an effective, selective inhibitor of Janus tyrosine kinase 3 which binds competitively to the JAK3 ATP site (pIC50: 6.8, 5.0, 4.7, and < 5.0 for JAK3, EGFR, JAK1 and CDK4 respectively).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
5 mg$21535 days
10 mg$38035 days
25 mg$89035 days
50 mg$1,67035 days
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Product Introduction

Bioactivity
Description
ZM 449829 is an effective, selective inhibitor of Janus tyrosine kinase 3 which binds competitively to the JAK3 ATP site (pIC50: 6.8, 5.0, 4.7, and < 5.0 for JAK3, EGFR, JAK1 and CDK4 respectively).
Chemical Properties
Molecular Weight182.222
FormulaC13H10O
Cas No.4452-06-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: ≥8.2 mg/mL
Ethanol: <1 mg/mL
H2O: <1 mg/mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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