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(S)-(-)-O-Demethylbuchenavianine

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Catalog No. T88434Cas No. 91147-18-1

(S)-(-)-O-Demethylbuchenavianine (Compound (S)-(−)-1), a flavonoidal alkaloid, serves as a potent inhibitor of CDKs, exhibiting IC 50 values of 0.03 μM for CDK1 and 0.05 μM for CDK5, respectively.

(S)-(-)-O-Demethylbuchenavianine
Other Forms of (S)-(-)-O-Demethylbuchenavianine:
(R)-(+)-O-DemethylbuchenavianineT884351364123-68-1
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(S)-(-)-O-Demethylbuchenavianine

😃Good
Catalog No. T88434Cas No. 91147-18-1
(S)-(-)-O-Demethylbuchenavianine (Compound (S)-(−)-1), a flavonoidal alkaloid, serves as a potent inhibitor of CDKs, exhibiting IC 50 values of 0.03 μM for CDK1 and 0.05 μM for CDK5, respectively.
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10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
(S)-(-)-O-Demethylbuchenavianine (Compound (S)-(−)-1), a flavonoidal alkaloid, serves as a potent inhibitor of CDKs, exhibiting IC 50 values of 0.03 μM for CDK1 and 0.05 μM for CDK5, respectively.
Chemical Properties
Molecular Weight351.40
FormulaC21H21NO4
Cas No.91147-18-1
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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