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AkaLumine hydrochloride

Name: AkaLumine hydrochloride
Brand: TargetMol
SKU: T18914
Price: 93 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T18914Cas No. 2558205-28-8

Alias AkaLumine hydrochloride (1176235-08-7 free base), AkaLumine hydrochloride

AkaLumine hydrochloride is a fluorescein analog with a Km value of 2.06 μM for recombinant fluorescent protein.

AkaLumine hydrochloride

🥰Excellent

Purity: 98.88%

Catalog No. T18914Alias AkaLumine hydrochloride (1176235-08-7 free base), AkaLumine hydrochlorideCas No. 2558205-28-8

AkaLumine hydrochloride is a fluorescein analog with a Km value of 2.06 μM for recombinant fluorescent protein.

Pack Size	Price	Availability
1 mg	$93	In Stock
5 mg	$228	In Stock
10 mg	$378	In Stock
25 mg	$639	In Stock
50 mg	$890	In Stock

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Purity:98.88%

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COA HPLC

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	AkaLumine hydrochloride is a fluorescein analog with a Km value of 2.06 μM for recombinant fluorescent protein.
Targets&IC50	Recombinant Fluc protein:2.06 μM
In vitro	In both LLC/luc and MDA-MB-231/Luc cells exposed to AkaLumine hydrochloride, the signal peaks at lower concentrations (starting from 2.5 μM). Conversely, the bioluminescence produced by D-luciferin and CycLuc1 continuously increases with concentration, without reaching saturation, even at 250 μM.[1]
In vivo	AkaLumine hydrochloride-treated mice 15 min after intravenous injection of LLC/luc cells at the dose of 5 mM, exhibit a 3.3-fold increase in detection sensitivity of disseminated cancer cells in the lung compared with the experimental control group. In the inverse order at an 8 h interval. AkaLumine hydrochloride displays about a fourfold increase in signals from lung metastasis compared with the experimental control group.[1]
Alias	AkaLumine hydrochloride (1176235-08-7 free base), AkaLumine hydrochloride

Chemical Properties

Molecular Weight	338.85
Formula	C₁₆H₁₉ClN₂O₂S
Cas No.	2558205-28-8
Smiles	Cl.CN(C)c1ccc(\C=C\C=C\C2=N[C@H](CS2)C(O)=O)cc1
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 45.0 mg/mL (132.8 mM), Sonication is recommended.

H2O: 25 mg/mL (73.77 mM）, Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9512 mL	14.7558 mL	29.5116 mL	147.5579 mL
5 mM	0.5902 mL	2.9512 mL	5.9023 mL	29.5116 mL
10 mM	0.2951 mL	1.4756 mL	2.9512 mL	14.7558 mL
20 mM	0.1476 mL	0.7378 mL	1.4756 mL	7.3779 mL
50 mM	0.0590 mL	0.2951 mL	0.5902 mL	2.9512 mL

DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0295 mL	0.1476 mL	0.2951 mL	1.4756 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

1176235-08-7 free base1176235-08-7AkaLumine Hydrochloride