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AKR1C3-IN-8

Catalog No. T61926

AKR1C3-IN-8 (Compound 5) is a potent and selective AKR1C3 inhibitor (IC50 = 0.069 μM) with demonstrated antitumor activity.

AKR1C3-IN-8

AKR1C3-IN-8

Catalog No. T61926
AKR1C3-IN-8 (Compound 5) is a potent and selective AKR1C3 inhibitor (IC50 = 0.069 μM) with demonstrated antitumor activity.
Pack SizePriceAvailabilityQuantity
25 mg$1,52010-14 weeks
50 mg$1,98010-14 weeks
100 mg$2,50010-14 weeks
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Product Introduction

Bioactivity
Description
AKR1C3-IN-8 (Compound 5) is a potent and selective AKR1C3 inhibitor (IC50 = 0.069 μM) with demonstrated antitumor activity.
In vitro
AKR1C3-IN-8 (Compound 5) exhibits antiproliferative effects with an IC50 of 52.06 ± 0.99 μM against the prostate cancer cell line 22rv1, and inhibits PSA expression and testosterone production within the 0-50 μM concentration range on 22rv1 cells [1].
Chemical Properties
Molecular Weight400.43
FormulaC23H20N4O3
Storage & Solubility Information
StorageShipping with blue ice.

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