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Anivamersen sodium

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Catalog No. T85654Cas No. 959716-31-5

Anivamersen sodium, a complementary sequence reversal oligonucleotide, serves as an RNA aptamer designed to reverse the anticoagulant effect of the parenteral factor IXa inhibitor pegnivacogin. Together, pegnivacogin—a coagulation factor IXa inhibiting RNA aptamer—and anivamersen comprise REG1, a novel anticoagulation system.

Anivamersen sodium

Anivamersen sodium

😃Good
Catalog No. T85654Cas No. 959716-31-5
Anivamersen sodium, a complementary sequence reversal oligonucleotide, serves as an RNA aptamer designed to reverse the anticoagulant effect of the parenteral factor IXa inhibitor pegnivacogin. Together, pegnivacogin—a coagulation factor IXa inhibiting RNA aptamer—and anivamersen comprise REG1, a novel anticoagulation system.
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Product Introduction

Bioactivity
Description
Anivamersen sodium, a complementary sequence reversal oligonucleotide, serves as an RNA aptamer designed to reverse the anticoagulant effect of the parenteral factor IXa inhibitor pegnivacogin. Together, pegnivacogin—a coagulation factor IXa inhibiting RNA aptamer—and anivamersen comprise REG1, a novel anticoagulation system.
Chemical Properties
Molecular Weight5269.1
FormulaC157H194N56Na14O103P14
Cas No.959716-31-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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