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Anti-inflammatory agent 41
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Catalog No. T85687Cas No. 2896204-90-1
The anti-inflammatory agent 41 (13a) markedly inhibits lipopolysaccharide (LPS)-induced expression of the proinflammatory cytokines IL-6 and TNF-α in J774A.1, THP-1, and LX-2 cells, while also preventing the activation of the NF-κB pathway [1].
Anti-inflammatory agent 41
😃Good
Catalog No. T85687Cas No. 2896204-90-1
The anti-inflammatory agent 41 (13a) markedly inhibits lipopolysaccharide (LPS)-induced expression of the proinflammatory cytokines IL-6 and TNF-α in J774A.1, THP-1, and LX-2 cells, while also preventing the activation of the NF-κB pathway [1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks |
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Chemical Properties
| Description | The anti-inflammatory agent 41 (13a) markedly inhibits lipopolysaccharide (LPS)-induced expression of the proinflammatory cytokines IL-6 and TNF-α in J774A.1, THP-1, and LX-2 cells, while also preventing the activation of the NF-κB pathway [1]. |
| In vitro | Anti-inflammatory agent 41 (13a) significantly reduced LPS-induced nuclear translocation of p65 in J774A.1 macrophages. |
| Molecular Weight | 543.57 |
| Formula | C33H25N3O5 |
| Cas No. | 2896204-90-1 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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