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Antibacterial agent 122
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Antibacterial agent 122
Catalog No. T60690Cas No. 109310-99-8
Antibacterial agent 122 (compound 15) is a thiourea derivative that can be used in the studies of tuberculosis. Antibacterial agent 122 shows low cytotoxicity as well as anti-mycobacterial activity [1].
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,520 | 6-8 weeks | |
| 50 mg | $1,980 | 6-8 weeks | |
| 100 mg | $2,500 | 6-8 weeks |
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Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Antibacterial agent 122 (compound 15) is a thiourea derivative that can be used in the studies of tuberculosis. Antibacterial agent 122 shows low cytotoxicity as well as anti-mycobacterial activity [1]. |
| In vitro | Antibacterial agent 122 (compound 15) (25-200 μM, 24 h) inhibits M. tuberculosis H37Rv with the MIC 50 value of 5.9 μM and inhibits NO production in LPS-stimulated RAW 264.7 cell cultures with an IC 50 value of 8.1μM [1]. Antibacterial agent 122 (compound 15) (25-200 μM) acts on NO scavenging with an IC 50 value of 184.2 μM, and almost completely inhibits iNOS expression in LPS-stimulated RAW264.7 macrophages at a concentration of 100 μM [1]. Antibacterial agent 122 (compound 15) (0-200 μM, 24 h) inhibits TNF-α and IL-1β production in LPS-stimulated macrophages with the IC 50 values of 28.4 μM and 47.9 μM, respectively [1]. Antibacterial agent 122 (compound 15) (25-100 μM, 4 days) inhibits M. tuberculosis M299 with an MIC 50 value of 24.7 μM [1]. |
| Molecular Weight | 302.35 |
| Formula | C15H14N2O3S |
| Cas No. | 109310-99-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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