Antifungal agent 37 is a heterocyclic disulfide that exhibits antifungal activity [1].

Antifungal agent 37, at a concentration of 50 μg/mL, exhibits inhibitory effects against a range of ten pathogenic fungi, achieving inhibition rates of 65.46% (R. solani), 98.56% (S. sclerotiorum), 41.99% (B. cinerea), 66.80% (F. graminearum), 36.70% (M. oryzae), 28.26% (P. capsici), 100% (A. flavus), 57.35% (P. expansum), 89.64% (M. fructicola), and 59.03% (R. stolonifer). The same agent demonstrates varying efficacies, with EC50 values reported at 10.67 μg/mL for R. solani, 10.10 μg/mL for S. sclerotiorum, 23.49 μg/mL for F. graminearum, and >10 μg/mL for A. flavus, 9.71 μg/mL for M. fructicola, 21.54 μg/mL for R. stolonifer. Furthermore, it exerts a superior antibacterial effect on X. oryzae compared to the benchmark control drug, with a minimum inhibitory concentration (MIC) of just 1.56 μg/mL [1].

Antifungal agent 37, administered via sprinkling at a concentration of 200 μg/mL for a period of 14 days, effectively suppresses rice bacterial blight in vivo [1].