Antitumor agent-149

Antitumor agent-149 (Compound 3), an analogue of Echinomycin, inhibits HIF-1α-mediated transcription, induces cancer cell apoptosis, and suppresses tumor growth in the SW620 xenograft mice model [1].

Catalog No. T85707Cas No. 2368983-54-2

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Antitumor agent-149

Catalog No. T85707Cas No. 2368983-54-2

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Product Introduction

Bioactivity

Description	Antitumor agent-149 (Compound 3), an analogue of Echinomycin, inhibits HIF-1α-mediated transcription, induces cancer cell apoptosis, and suppresses tumor growth in the SW620 xenograft mice model [1].
In vitro	Antitumor agent-149 exhibits cytotoxicity against SW620 and MIA PaCa-2 cells, with IC₅₀ values of 0.85 nM and 1.4 nM, respectively [1].

Chemical Properties

Molecular Weight	1085.19
Formula	C₅₂H₆₄N₁₀O₁₄S
Cas No.	2368983-54-2

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