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AS115

Catalog No. T85733Cas No. 926657-43-4

AS115, a potent and selective KIAA1363 inactivator, exhibits an IC50 of 150 nM. It targets KIAA1363, a 2-acetyl monoacylglycerol ether (MAGE) hydrolase, which is notably upregulated in aggressive cancers across diverse tissues [1] [2].

AS115

AS115

Catalog No. T85733Cas No. 926657-43-4
AS115, a potent and selective KIAA1363 inactivator, exhibits an IC50 of 150 nM. It targets KIAA1363, a 2-acetyl monoacylglycerol ether (MAGE) hydrolase, which is notably upregulated in aggressive cancers across diverse tissues [1] [2].
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10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
AS115, a potent and selective KIAA1363 inactivator, exhibits an IC50 of 150 nM. It targets KIAA1363, a 2-acetyl monoacylglycerol ether (MAGE) hydrolase, which is notably upregulated in aggressive cancers across diverse tissues [1] [2].
In vitro
AS115 (10 μM, 4 h) significantly reduces the formation of MAGE, alkyl-lysophosphatidylcholine, and alkyl-lysophosphatidic acid in SKOV3 cells [1].
Chemical Properties
Molecular Weight381.48
FormulaC21H32FNO4
Cas No.926657-43-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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