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Autotaxin-IN-6 (compound 23) is a potent inhibitor of autotaxin (ATX), exhibiting an IC50 of 30 nM, and attenuates cell migration with potential applications in anticancer research [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 6-8 weeks | |
50 mg | $1,980 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | Autotaxin-IN-6 (compound 23) is a potent inhibitor of autotaxin (ATX), exhibiting an IC50 of 30 nM, and attenuates cell migration with potential applications in anticancer research [1]. |
Targets&IC50 | ATX:30 nM |
In vitro | Autotaxin-IN-6 (compound 23) effectively inhibits ATX-induced activity in HeLa cells, significantly reducing LPA1 internalization by approximately 75% [1], while also impeding LPA1 activation and disrupting downstream Gαi- and PI3K-dependent signaling pathways [1]. |
Molecular Weight | 595.62 |
Formula | C35H54BNO6 |
Cas No. | 2800898-98-8 |
Storage | Shipping with blue ice. |
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