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BAOP-16

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Catalog No. T202029
Alias BAOP16, BAOP 16

BAOP-16 is a near-infrared fluorescent probe (NIRF) designed specifically to target various soluble Aβ aggregates. This probe has a "y" shaped molecular structure, and its fluorescence intensity significantly increases when it binds to soluble Aβ aggregates in the near-infrared region, exhibiting high affinity. Additionally, BAOP-16 is capable of detecting Aβ oligomers in the brains of Aβ-inoculated model mice. In vivo fluorescence imaging studies of BAOP-16 have shown that the brains of AD model mice exhibit significantly higher fluorescence signals than those of wild-type mice. These findings indicate that BAOP-16 can be used for in vivo NIRF imaging to effectively identify various soluble Aβ aggregates.

BAOP-16

BAOP-16

😃Good
Catalog No. T202029Alias BAOP16, BAOP 16
BAOP-16 is a near-infrared fluorescent probe (NIRF) designed specifically to target various soluble Aβ aggregates. This probe has a "y" shaped molecular structure, and its fluorescence intensity significantly increases when it binds to soluble Aβ aggregates in the near-infrared region, exhibiting high affinity. Additionally, BAOP-16 is capable of detecting Aβ oligomers in the brains of Aβ-inoculated model mice. In vivo fluorescence imaging studies of BAOP-16 have shown that the brains of AD model mice exhibit significantly higher fluorescence signals than those of wild-type mice. These findings indicate that BAOP-16 can be used for in vivo NIRF imaging to effectively identify various soluble Aβ aggregates.
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Product Introduction

Bioactivity
Description
BAOP-16 is a near-infrared fluorescent probe (NIRF) designed specifically to target various soluble Aβ aggregates. This probe has a "y" shaped molecular structure, and its fluorescence intensity significantly increases when it binds to soluble Aβ aggregates in the near-infrared region, exhibiting high affinity. Additionally, BAOP-16 is capable of detecting Aβ oligomers in the brains of Aβ-inoculated model mice. In vivo fluorescence imaging studies of BAOP-16 have shown that the brains of AD model mice exhibit significantly higher fluorescence signals than those of wild-type mice. These findings indicate that BAOP-16 can be used for in vivo NIRF imaging to effectively identify various soluble Aβ aggregates.
AliasBAOP16, BAOP 16
Chemical Properties
Molecular Weight533.42
FormulaC33H30BF2N3O
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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