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BAY-678 racemate

Name: BAY-678 racemate
Brand: TargetMol
SKU: T19202
Rating: 4.5 (1 reviews)

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Catalog No. T19202Cas No. 675103-35-2

BAY-678 racemate is a racemate of BAY-678, an orally bioavailable, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE; IC50: 20 nM).

BAY-678 racemate

😃Good

Catalog No. T19202Cas No. 675103-35-2

BAY-678 racemate is a racemate of BAY-678, an orally bioavailable, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE; IC50: 20 nM).

Pack Size	Price	Availability
25 mg	$1,520	6-8 weeks
50 mg	$1,980	6-8 weeks
100 mg	$2,500	6-8 weeks

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Product Introduction

Bioactivity

Description

BAY-678 racemate is a racemate of BAY-678, an orally bioavailable, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE; IC50: 20 nM).

Chemical Properties

Molecular Weight	400.35
Formula	C₂₀H₁₅F₃N₄O₂
Cas No.	675103-35-2
Relative Density.	1.42 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 150 mg/mL (374.67 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4978 mL	12.4891 mL	24.9781 mL	124.8907 mL
5 mM	0.4996 mL	2.4978 mL	4.9956 mL	24.9781 mL
10 mM	0.2498 mL	1.2489 mL	2.4978 mL	12.4891 mL
20 mM	0.1249 mL	0.6245 mL	1.2489 mL	6.2445 mL
50 mM	0.0500 mL	0.2498 mL	0.4996 mL	2.4978 mL
100 mM	0.0250 mL	0.1249 mL	0.2498 mL	1.2489 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

BAY 678 racemateBAY-678 racemateBAY678 racemate