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BC-1293

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Catalog No. T89425Cas No. 1219395-86-4

BC-1293 is an inhibitor of the E3 ligase subunit FBXO24. It disrupts the interaction between FBXO24 and aspartyl-tRNA synthetase (DARS2), enhancing DARS2 levels. Additionally, BC-1293 increases levels of IL-1β, IL-9, MIP-2, and TNF α, demonstrating immunostimulatory activity in mice.

BC-1293

BC-1293

😃Good
Catalog No. T89425Cas No. 1219395-86-4
BC-1293 is an inhibitor of the E3 ligase subunit FBXO24. It disrupts the interaction between FBXO24 and aspartyl-tRNA synthetase (DARS2), enhancing DARS2 levels. Additionally, BC-1293 increases levels of IL-1β, IL-9, MIP-2, and TNF α, demonstrating immunostimulatory activity in mice.
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
BC-1293 is an inhibitor of the E3 ligase subunit FBXO24. It disrupts the interaction between FBXO24 and aspartyl-tRNA synthetase (DARS2), enhancing DARS2 levels. Additionally, BC-1293 increases levels of IL-1β, IL-9, MIP-2, and TNF α, demonstrating immunostimulatory activity in mice.
Chemical Properties
Molecular Weight492.59
FormulaC26H28N4O4S
Cas No.1219395-86-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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