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Bis-CH2-PEG2-acid is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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500 mg | Inquiry | Backorder |
Description | Bis-CH2-PEG2-acid is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands linked together—one targeting an E3 ubiquitin ligase and the other targeting the desired protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Alias | Bis-CH2-PEG2-acid |
Molecular Weight | 192.167 |
Formula | C7H12O6 |
Cas No. | 2250056-38-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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