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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Bis-PEG14-acid, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands linked by a connector: one ligand targets an E3 ubiquitin ligase and the other targets the specific protein. They utilize the intracellular ubiquitin-proteasome system for the selective degradation of target proteins[1]. |
Molecular Weight | 734.82 |
Formula | C32H62O18 |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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