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BnO-PEG4-OH

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Catalog No. T14699Cas No. 86259-87-2

BnO-PEG4-OH is a PEG-based linker for PROTACs [degrader molecules], joining two essential ligands to facilitate selective protein degradation via the ubiquitin-proteasome system.

BnO-PEG4-OH

BnO-PEG4-OH

😃Good
Catalog No. T14699Cas No. 86259-87-2
BnO-PEG4-OH is a PEG-based linker for PROTACs [degrader molecules], joining two essential ligands to facilitate selective protein degradation via the ubiquitin-proteasome system.
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100 mgInquiry7-10 days
500 mgInquiry7-10 days
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Product Introduction

Bioactivity
Description
BnO-PEG4-OH is a PEG-based linker for PROTACs [degrader molecules], joining two essential ligands to facilitate selective protein degradation via the ubiquitin-proteasome system.
In vitro
PROTACs consist of two distinct ligands joined by a linker: one ligand targets an E3 ubiquitin ligase, while the other binds to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Chemical Properties
Molecular Weight284.35
FormulaC15H24O5
Cas No.86259-87-2
Relative Density.1.09 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

PEGsBnO-PEG4-OHBnO-PEG-4-OHBnOPEG4OHBnO PEG4 OH
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