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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,670 | 6-8 weeks | |
50 mg | $2,180 | 6-8 weeks | |
100 mg | $2,800 | 6-8 weeks |
Description | BPH-652 is an S. aureus dehydrosqualene synthase (CrtM) inhibitor (Ki: 1.5 nM; IC50: 100-300 nM for S. aureus pigment formation). |
In vivo | BPH-652 treatment (0.5 mg twice per day (days ?1, 0, 1, and 2), i.p.) significantly lowers S. aureus bacterial counts in the kidneys of the mice than those of the control group, with 8 of 13 below the detection threshold, versus only 2 of 14 in the control group; on average, this result corresponds to a 98% decrease in surviving bacteria in the treatment group. |
Molecular Weight | 503.65 |
Formula | C16H19K3O7PS |
Cas No. | 157124-84-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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