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BQ7859

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Catalog No. T203144

BQ7859 is a probe designed to target PSMA, equipped with a NOTA chelator, offering exceptional imaging capabilities. It can be labeled with various radionuclides such as [68Ga], [18F], [55Co], and [111In]. In mouse prostate cancer xenograft models, BQ7859 (labeled with [111In]) effectively accumulates in tumor regions through a PSMA-dependent mechanism, providing high-contrast tumor imaging. This compound holds promise for research in prostate cancer imaging, particularly in the areas of positron emission tomography (PET) and single-photon emission computed tomography (SPECT). Additionally, BQ7859 can be used in the synthesis or study of radionuclide conjugate drugs (RDC).

BQ7859

BQ7859

😃Good
Catalog No. T203144
BQ7859 is a probe designed to target PSMA, equipped with a NOTA chelator, offering exceptional imaging capabilities. It can be labeled with various radionuclides such as [68Ga], [18F], [55Co], and [111In]. In mouse prostate cancer xenograft models, BQ7859 (labeled with [111In]) effectively accumulates in tumor regions through a PSMA-dependent mechanism, providing high-contrast tumor imaging. This compound holds promise for research in prostate cancer imaging, particularly in the areas of positron emission tomography (PET) and single-photon emission computed tomography (SPECT). Additionally, BQ7859 can be used in the synthesis or study of radionuclide conjugate drugs (RDC).
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Product Introduction

Bioactivity
Description
BQ7859 is a probe designed to target PSMA, equipped with a NOTA chelator, offering exceptional imaging capabilities. It can be labeled with various radionuclides such as [68Ga], [18F], [55Co], and [111In]. In mouse prostate cancer xenograft models, BQ7859 (labeled with [111In]) effectively accumulates in tumor regions through a PSMA-dependent mechanism, providing high-contrast tumor imaging. This compound holds promise for research in prostate cancer imaging, particularly in the areas of positron emission tomography (PET) and single-photon emission computed tomography (SPECT). Additionally, BQ7859 can be used in the synthesis or study of radionuclide conjugate drugs (RDC).
Chemical Properties
Molecular Weight1276.43
FormulaC62H89N11O18
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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