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BR351 precursor

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Catalog No. T10598Cas No. 960113-89-7

BR351 precursor is a precursor of BR351, a brain-penetrant MMP inhibitor [IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9, and MMP13].

BR351 precursor

BR351 precursor

😃Good
Catalog No. T10598Cas No. 960113-89-7
BR351 precursor is a precursor of BR351, a brain-penetrant MMP inhibitor [IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9, and MMP13].
Pack SizePriceAvailabilityQuantity
25 mg$1,5206-8 weeks
50 mg$1,9806-8 weeks
100 mg$2,5006-8 weeks
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Product Introduction

Bioactivity
Description
BR351 precursor is a precursor of BR351, a brain-penetrant MMP inhibitor [IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9, and MMP13].
Chemical Properties
Molecular Weight576.68
FormulaC27H32N2O8S2
Cas No.960113-89-7
Relative Density.1.325 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

BR351 precursorBR-351 precursor
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