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BTK-IN-34

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Catalog No. T85926Cas No. 3016419-52-3

BTK-IN-34 (compound 9h; 1-50 μM; 24 小时) reduces levels of pBTK, pERK 1/2 (Thr202/Tyr204), and p-p38 (Thr180/Tyr182) in RAMOS cells [1]. This compound shows selective cytotoxicity towards BTK-high RAMOS cells with an IC50 of 2.75 μM. Western Blot analysis was conducted on RAMOS cells with concentrations of 1 μM, 10 μM, and 50 μM over a 24-hour incubation, resulting in decreased pBTK (Tyr223) levels.

BTK-IN-34

BTK-IN-34

😃Good
Catalog No. T85926Cas No. 3016419-52-3
BTK-IN-34 (compound 9h; 1-50 μM; 24 小时) reduces levels of pBTK, pERK 1/2 (Thr202/Tyr204), and p-p38 (Thr180/Tyr182) in RAMOS cells [1]. This compound shows selective cytotoxicity towards BTK-high RAMOS cells with an IC50 of 2.75 μM. Western Blot analysis was conducted on RAMOS cells with concentrations of 1 μM, 10 μM, and 50 μM over a 24-hour incubation, resulting in decreased pBTK (Tyr223) levels.
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Product Introduction

Bioactivity
Description
BTK-IN-34 (compound 9h; 1-50 μM; 24 小时) reduces levels of pBTK, pERK 1/2 (Thr202/Tyr204), and p-p38 (Thr180/Tyr182) in RAMOS cells [1]. This compound shows selective cytotoxicity towards BTK-high RAMOS cells with an IC50 of 2.75 μM. Western Blot analysis was conducted on RAMOS cells with concentrations of 1 μM, 10 μM, and 50 μM over a 24-hour incubation, resulting in decreased pBTK (Tyr223) levels.
In vitro
BTK-IN-34 (compound 9h; 1-50 μM; 24 小时) reduces levels of pBTK, pERK 1/2 (Thr202/Tyr204), and p-p38 (Thr180/Tyr182) in RAMOS cells [1]. This compound shows selective cytotoxicity towards BTK-high RAMOS cells with an IC50 of 2.75 μM. Western Blot analysis was conducted on RAMOS cells with concentrations of 1 μM, 10 μM, and 50 μM over a 24-hour incubation, resulting in decreased pBTK (Tyr223) levels.
Chemical Properties
Molecular Weight431.55
FormulaC22H29N3O4S
Cas No.3016419-52-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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