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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $1,760 | Backorder |
Description | C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) is the predominant sulfate analog in the mature myelin sheath. C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) interacted with C-type lectin and immunoglobulin-like receptors to give the highest affinity for LMIR5. Galactosylceramide (d18:1/24:1(15Z)) induces MCP-1 production by basophils, which activates NFAT by increasing LMIR5, but not mast cells .C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) binds in vitro to CD1d binding and increased the proliferation of free mouse splenocytes. |
In vitro | The relationship between structure and activity (SAR) of newly synthesized sulfatide isoforms C24:1 was evaluated. The basal IDO1 expression was significantly increased by C24:1 sulfatide (+87 ± 7% and +50 ± 5% at 1μΜ, respectively) over negative controls ; These effects functionally correlated with changes in IDO1 activity: l-kynurenine contents in the culture media were significantly increased by C24:1 sulfatide (+61 ± 8% and +48 ± 4% at 1μM, respectively) over negative controls.[2] |
Alias | C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) |
Molecular Weight | 890.3 |
Formula | C48H91NO11S |
Cas No. | 151057-28-2 |
Storage | store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | Chloroform:Methanol (5:1): Soluble |
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