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C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))

Name: C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))
Brand: TargetMol
SKU: T38285
Rating: 4.5 (1 reviews)

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Catalog No. T38285Cas No. 151057-28-2

Alias C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))

C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) is the predominant sulfate analog in the mature myelin sheath. C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) interacted with C-type lectin and immunoglobulin-like receptors to give the highest affinity for LMIR5. Galactosylceramide (d18:1/24:1(15Z)) induces MCP-1 production by basophils, which activates NFAT by increasing LMIR5, but not mast cells .C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) binds in vitro to CD1d binding and increased the proliferation of free mouse splenocytes.

C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))

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Catalog No. T38285Alias C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))Cas No. 151057-28-2

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Product Introduction

Bioactivity

Description	C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) is the predominant sulfate analog in the mature myelin sheath. C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) interacted with C-type lectin and immunoglobulin-like receptors to give the highest affinity for LMIR5. Galactosylceramide (d18:1/24:1(15Z)) induces MCP-1 production by basophils, which activates NFAT by increasing LMIR5, but not mast cells .C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) binds in vitro to CD1d binding and increased the proliferation of free mouse splenocytes.
In vitro	The relationship between structure and activity (SAR) of newly synthesized sulfatide isoforms C24:1 was evaluated. The basal IDO1 expression was significantly increased by C24:1 sulfatide (+87 ± 7% and +50 ± 5% at 1μΜ, respectively) over negative controls ; These effects functionally correlated with changes in IDO1 activity: l-kynurenine contents in the culture media were significantly increased by C24:1 sulfatide (+61 ± 8% and +48 ± 4% at 1μM, respectively) over negative controls.[2]
Alias	C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))

Chemical Properties

Molecular Weight	890.3
Formula	C₄₈H₉₁NO₁₁S
Cas No.	151057-28-2
Smiles	O(C[C@@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@H]1[C@H](O)[C@@H](OS(=O)(=O)O)[C@@H](O)[C@@H](CO)O1

Storage & Solubility Information

Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	Chloroform:Methanol (5:1): Soluble

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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mix well and clarify

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Keywords

Nuclear factor of activated Tcells (NFAT)MCP-1C24:1 3'-sulfo Galactosylceramide (d18:1/24:1)C24:1 3'sulfo Galactosylceramide (d18:1/24:1(15Z))C-24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))C24:1 3' sulfo Galactosylceramide (d18:1/24:1(15Z))

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