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Carboxy-PEG4-phosphonic acid ethyl ester is a PEG-based PROTAC linker used in the synthesis of PROTACs, serving as an integral compound [1].
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Description | Carboxy-PEG4-phosphonic acid ethyl ester is a PEG-based PROTAC linker used in the synthesis of PROTACs, serving as an integral compound [1]. |
In vitro | PROTACs are composed of two distinct ligands linked together: one targets an E3 ubiquitin ligase and the other binds to the target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 386.38 |
Formula | C15H31O9P |
Cas No. | 1964503-39-6 |
Relative Density. | 1.160 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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