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Cbz-NH-PEG36-C2-acid is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands vital for PROTAC molecule formation. It enables selective protein degradation by utilizing the cell's ubiquitin-proteasome system.
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500 mg | Inquiry | Backorder |
Description | Cbz-NH-PEG36-C2-acid is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands vital for PROTAC molecule formation. It enables selective protein degradation by utilizing the cell's ubiquitin-proteasome system. |
In vitro | PROTACs, consisting of two ligands linked together—one targeting an E3 ubiquitin ligase and the other the target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 1809.12 |
Formula | C83H157NO40 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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