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Description | CDK-IN-6, a pyrazolo[1,5-a]pyrimidine compound, exhibits potent anticancer activities as a CDK inhibitor[1]. |
In vitro | CDKs, including CDK1, CDK2, CDK3, CDK4, CDK5, CDK6, CDK7, CDK8, among others, play specific roles in the progression of the cell cycle, being categorized into G1, S, or G2M phase enzymes. The unchecked proliferation characteristic of cancer cells often involves the frequent misregulation of CDK function in various significant solid tumors[1]. |
Molecular Weight | 380.49 |
Formula | C21H28N6O |
Cas No. | 779353-02-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (131.41 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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