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CDK4/6-IN-19 (Compound II-7) serves as an inhibitor of CDK4 and CDK6, exhibiting IC 50 values of 0.2 nM and 5.0 nM, respectively. Additionally, it suppresses cell proliferation and is applicable in cancer research.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | CDK4/6-IN-19 (Compound II-7) serves as an inhibitor of CDK4 and CDK6, exhibiting IC 50 values of 0.2 nM and 5.0 nM, respectively. Additionally, it suppresses cell proliferation and is applicable in cancer research. |
Targets&IC50 | CDK4:0.2 nM, CDK6:5.0 nM |
In vitro | CDK4/6-IN-19 inhibits the proliferation of MCF7 and T47D cells, with IC50 values of 217 and 212 nM, respectively [1]. |
Molecular Weight | 508.01 |
Formula | C23H27ClFN5O3S |
Cas No. | 3033950-86-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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