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CDK4/6-IN-20

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Catalog No. T88119Cas No. 3033950-84-1

CDK4/6-IN-20 (Compound II-5) is an inhibitor targeting CDK4 and CDK6, exhibiting IC 50 values of 1.9 and 14.2 nM, respectively. Additionally, it suppresses cell proliferation and is applicable in cancer research.

CDK4/6-IN-20

CDK4/6-IN-20

😃Good
Catalog No. T88119Cas No. 3033950-84-1
CDK4/6-IN-20 (Compound II-5) is an inhibitor targeting CDK4 and CDK6, exhibiting IC 50 values of 1.9 and 14.2 nM, respectively. Additionally, it suppresses cell proliferation and is applicable in cancer research.
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
CDK4/6-IN-20 (Compound II-5) is an inhibitor targeting CDK4 and CDK6, exhibiting IC 50 values of 1.9 and 14.2 nM, respectively. Additionally, it suppresses cell proliferation and is applicable in cancer research.
Targets&IC50
CDK4:1.9 nM, CDK6:14.2 nM
In vitro
CDK4/6-IN-20 inhibits the proliferation of MCF7 and T47D cells, with IC_50 values of 169 nM and 92 nM, respectively [1].
Chemical Properties
Molecular Weight421.47
FormulaC23H24FN5O2
Cas No.3033950-84-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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