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CDKL2-IN-1

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Catalog No. T88993Cas No. 2471972-15-1

CDK-IN-14 (Compound 9) serves as a potent and selective inhibitor of CDKL2 (Cyclin-dependent kinase-like 2), exhibiting an IC50 of 460 nM. Linked to biological processes such as tumor formation, development, and viral infections, CDKL2 is a substantial focus in the field. CDK-IN-14 holds promise as a powerful tool for the exploration of CDKL2s biological functions, potentially advancing research in areas like cancer and infectious diseases.

CDKL2-IN-1

CDKL2-IN-1

😃Good
Catalog No. T88993Cas No. 2471972-15-1
CDK-IN-14 (Compound 9) serves as a potent and selective inhibitor of CDKL2 (Cyclin-dependent kinase-like 2), exhibiting an IC50 of 460 nM. Linked to biological processes such as tumor formation, development, and viral infections, CDKL2 is a substantial focus in the field. CDK-IN-14 holds promise as a powerful tool for the exploration of CDKL2s biological functions, potentially advancing research in areas like cancer and infectious diseases.
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10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
CDK-IN-14 (Compound 9) serves as a potent and selective inhibitor of CDKL2 (Cyclin-dependent kinase-like 2), exhibiting an IC50 of 460 nM. Linked to biological processes such as tumor formation, development, and viral infections, CDKL2 is a substantial focus in the field. CDK-IN-14 holds promise as a powerful tool for the exploration of CDKL2s biological functions, potentially advancing research in areas like cancer and infectious diseases.
In vitro
CDK-IN-14 (0-4 μM, 1 hour) disrupts downstream signaling in primary rat neurons mediated by CDKL2 by inhibiting CDKL2, thereby demonstrating inhibitory activity towards CDKL2.
Chemical Properties
Molecular Weight426.53
FormulaC22H26N4O3S
Cas No.2471972-15-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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