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CFTR corrector 13

Catalog No. T89629

CFTRcorrector 13 (SVQ18) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector with an EC50 value of 3.14 μM. This compound enhances the function of CFTR channels, particularly when used in conjunction with Lumacaftor, leading to a dose-dependent increase in CFTR activity. CFTRcorrector 13 is utilized in research related to cystic fibrosis (CF) and other CFTR-associated diseases.

CFTR corrector 13

CFTR corrector 13

Catalog No. T89629
CFTRcorrector 13 (SVQ18) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector with an EC50 value of 3.14 μM. This compound enhances the function of CFTR channels, particularly when used in conjunction with Lumacaftor, leading to a dose-dependent increase in CFTR activity. CFTRcorrector 13 is utilized in research related to cystic fibrosis (CF) and other CFTR-associated diseases.
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Product Introduction

Bioactivity
Description
CFTRcorrector 13 (SVQ18) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector with an EC50 value of 3.14 μM. This compound enhances the function of CFTR channels, particularly when used in conjunction with Lumacaftor, leading to a dose-dependent increase in CFTR activity. CFTRcorrector 13 is utilized in research related to cystic fibrosis (CF) and other CFTR-associated diseases.
Chemical Properties
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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