Shopping Cart
- Remove All
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | Backorder |
Description | CGP-53153 is a steroidal inhibitor of 5 alpha-reductase (IC50s: 36 and 262 nM in rat and human prostatic tissue). |
In vitro | CGP-53153 competitively inhibits rat microsomal 5 alpha-reductase from the prostate (IC50: 36 nM) compared to the reference compound finasteride (IC50: 11 nM). |
In vivo | CGP-53153, administered orally at a dose of 0.01 mg/kg, significantly reduces T-propionate-induced prostate growth. Further, it notably lowers prostate weight by 31% and 37% at doses of 3 and 10 mg/kg, respectively. A 12-week treatment regimen with CGP-53153 diminishes prostate volume by over 70% in individual dogs without affecting body weight or the weight of any tested organ. |
Molecular Weight | 383.53 |
Formula | C23H33N3O2 |
Cas No. | 149281-19-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.