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Description | Cl-PEG6-acid is a PEG-based linker for PROTACs that connects two essential ligands, crucial for the formation of PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs comprise two distinct ligands linked together: one targets an E3 ubiquitin ligase, and the other binds to the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs facilitate the selective degradation of target proteins [1]. |
Alias | Cl-PEG6-acid |
Molecular Weight | 358.81 |
Formula | C14H27ClO8 |
Cas No. | 2365309-92-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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