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Cladophorol A is a cGAS inhibitor that obstructs its activity by binding to the conserved adenosine nucleotide binding site of cGAS. It effectively suppresses the overactivation of the cGAS-STING pathway at non-cytotoxic concentrations, with an IC50 of 370 nM. Cladophorol A holds potential for research into inflammatory diseases linked to the overactivation of the cGAS-STING pathway.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | Cladophorol A is a cGAS inhibitor that obstructs its activity by binding to the conserved adenosine nucleotide binding site of cGAS. It effectively suppresses the overactivation of the cGAS-STING pathway at non-cytotoxic concentrations, with an IC50 of 370 nM. Cladophorol A holds potential for research into inflammatory diseases linked to the overactivation of the cGAS-STING pathway. |
Molecular Weight | 260.2 |
Formula | C13H8O6 |
Cas No. | 146776-30-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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