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COX-2-IN-16

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Catalog No. T61821Cas No. 1610894-92-2

COX-2-IN-16 (compound 2b) is a potent, selective, and orally active inhibitor of cyclooxygenase-2 (COX-2) with an IC50 value of 102 μM, effectively reducing nitric oxide (NO) production and demonstrating anti-inflammatory activity [1].

COX-2-IN-16

COX-2-IN-16

😃Good
Catalog No. T61821Cas No. 1610894-92-2
COX-2-IN-16 (compound 2b) is a potent, selective, and orally active inhibitor of cyclooxygenase-2 (COX-2) with an IC50 value of 102 μM, effectively reducing nitric oxide (NO) production and demonstrating anti-inflammatory activity [1].
Pack SizePriceAvailabilityQuantity
25 mg$1,5206-8 weeks
50 mg$1,9806-8 weeks
100 mg$2,5006-8 weeks
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Product Introduction

Bioactivity
Description
COX-2-IN-16 (compound 2b) is a potent, selective, and orally active inhibitor of cyclooxygenase-2 (COX-2) with an IC50 value of 102 μM, effectively reducing nitric oxide (NO) production and demonstrating anti-inflammatory activity [1].
In vivo
Administering COX-2-IN-16 (compound 2b) at 100 mg/kg orally results in a significant 42% reduction in edema formation in a rat paw edema model [1].
Chemical Properties
Molecular Weight394.22
FormulaC19H12BrN3O2
Cas No.1610894-92-2
Storage & Solubility Information
StorageShipping with blue ice.

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