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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 6-8 weeks | |
50 mg | $1,980 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | COX-2-IN-20 (Compound 5d) is a selective and orally active inhibitor of COX-2 (IC 50 = 17.9 nM) with anti-inflammatory activity [1]. |
In vitro | COX-2-IN-20 (Compound 5d) has potential anti-inflammatory activity against inhibition of NO in LPS-induced RAW 264.7 cell with an IC 50 of 2.87 μM [1]. |
In vivo | COX-2-IN-20 (Compound 5d) (5 mg/kg) shows better anti-inflammation and gastric protection in vivo than 10 mg/kg indomethacin [1]. |
Molecular Weight | 269.66 |
Formula | C11H9ClFN3O2 |
Cas No. | 2529451-43-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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