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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | DBCO-NHCO-PEG6-amine is a PEG-based linker used in PROTACs that joins two essential ligands for PROTAC molecule formation, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase, and the other interacts with the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 611.73 |
Formula | C33H45N3O8 |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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