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DDAO-C6
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Catalog No. T82600Cas No. 2102418-90-4
DDAO-C6, a cridone ester derivative, serves as a highly specific fluorescent probe for detecting human serum albumin (HSA). Additionally, it functions as an enzymatically activatable near-infrared fluorescent probe, facilitating the visual detection of endogenous lipase produced by gut microbes (Ex/Em=600/658 nm) [1] [2].
DDAO-C6
😃Good
Catalog No. T82600Cas No. 2102418-90-4
DDAO-C6, a cridone ester derivative, serves as a highly specific fluorescent probe for detecting human serum albumin (HSA). Additionally, it functions as an enzymatically activatable near-infrared fluorescent probe, facilitating the visual detection of endogenous lipase produced by gut microbes (Ex/Em=600/658 nm) [1] [2].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | DDAO-C6, a cridone ester derivative, serves as a highly specific fluorescent probe for detecting human serum albumin (HSA). Additionally, it functions as an enzymatically activatable near-infrared fluorescent probe, facilitating the visual detection of endogenous lipase produced by gut microbes (Ex/Em=600/658 nm) [1] [2]. |
| In vitro | DDAO-C6 (10 μM; 30 min; 37 ℃) exhibits a linear correlation between fluorescence intensity and lipase levels (0-50 μg/mL), yielding a red fluorescent signal upon interaction with active lipase [1]. |
| In vivo | DDAO-C6 serves as a tool for swiftly pinpointing and cultivating lipase-producing fungal strains within human fecal intestinal microbiota, representing a promising approach for the biological study of gut microbes [2]. |
| Molecular Weight | 420.33 |
| Formula | C22H23Cl2NO3 |
| Cas No. | 2102418-90-4 |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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