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Dextromethorphan

Name: Dextromethorphan
Brand: TargetMol
SKU: T0262L2
Price: 213 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0262L2Cas No. 125-71-3

Alias RACEMETHORPHAN, Levomethorphan

Dextromethorphan is a noncompetitive NMDA receptor antagonist and sigma-1 agonist that was approved by the FDA in 1958 for use as a cough suppressant.

Dextromethorphan

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Purity: 99.91%

Catalog No. T0262L2Alias RACEMETHORPHAN, LevomethorphanCas No. 125-71-3

Dextromethorphan is a noncompetitive NMDA receptor antagonist and sigma-1 agonist that was approved by the FDA in 1958 for use as a cough suppressant.

Pack Size	Price	Availability	Quantity
1 mL x 10 mM (in DMSO)	$213	In Stock

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Purity:99.91%

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COA HPLC HNMR

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Product Introduction

Bioactivity

Description	Dextromethorphan is a noncompetitive NMDA receptor antagonist and sigma-1 agonist that was approved by the FDA in 1958 for use as a cough suppressant.
In vitro	METHODS: Dextromethorphan (50-400 μM) or LK3 (25-200 μM) was preincubated with platelets for 3 min at 37°C, then inducer was added for 6 min to trigger TXB2. RESULTS Treatment with Dextromethorphan significantly inhibited collagen-stimulated formation of TXB2. [3]
Alias	RACEMETHORPHAN, Levomethorphan

Chemical Properties

Molecular Weight	271.4
Formula	C₁₈H₂₅NO
Cas No.	125-71-3
Smiles	O(C)C=1C=C2[C@]34[C@@]([C@](CC2=CC1)(N(C)CC3)[H])(CCCC4)[H]
Relative Density.	1.11 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 7.33 mg/ml (27.02 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6846 mL	18.4230 mL	36.8460 mL	184.2299 mL
5 mM	0.7369 mL	3.6846 mL	7.3692 mL	36.8460 mL
10 mM	0.3685 mL	1.8423 mL	3.6846 mL	18.4230 mL
20 mM	0.1842 mL	0.9211 mL	1.8423 mL	9.2115 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Keywords

Dextromethorphan